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The Myth of Chronic Vitamin D Deficiency in Blacks

Vitamin D deficiency: symptoms 

Symptômes de déficience en vitamine D
Symptômes de déficience en vitamine D

eumelanin(black skin melanin)is essential for UV protectionwhich cause skin cancer by damaging DNA. Black skin blocks twice as much UV rays as white skin. Melanocytes in black skin are more resistant to damage and supply melanin more sustainably. Melanin also has an action against free radicals (chemical molecules contributing to aging and disease) Dark skin, which contains more melanin than light skin, is better protected against UV-induced damage; melanin in black skin is twice as effective compared to white skin in inhibiting UV radiation.

Thanks to melanin (eumelanin), black skin absorbs UV rays from the sun, while white skin devoid of melanin reflects UV rays from the sun and therefore cannot fix calcium because it is the vitamin D produced by the exposure to the sun which allows its fixation in the bones. The consequence of this lack of calcium fixation in whites will cause osteoporosis (bone disease).


Vitamin D is produced by exposure to the sun.The skin is believed to convert sunlight into vitamin D because of 7-dehydrocholesterol (lipid in blood plasma converted to vitamin D3 in the skin). Vitamin D (D2, D3) has many benefits for humans both physiologically and emotionally. Here are the most important: It increases the strength of bones and teeth by allowing the body to fix calcium, Strengthens the immune system, Reduces the risk of cancer, Fights against heart disease, Reduces inflammation, Reduces the risk of diabetes type 2, Blocks radiation from radiation, Keeps you mentally alert, Works against occasional depression, Encourages emotional stability.

Dark skin, which contains more eumelanin than light skin, is better protected against UV-induced damage, and eumelanin (melanin in blacks) is considered superior to pheomelanin (pseudo-melanin in whites) in its photoprotective properties.

However, skin pigmentation has been reported to significantly reduce vitamin D3 synthesis, black-skinned people require at least 6 times greater amounts of UV (sun) radiation to increase circulating levels. of vitamin D3 than those with white skin. It has also been reported that many African Americans who live in northern regions of the United States suffer from severe vitamin D deficiencies despite vitamin D supplementation; It has been reported that black people need vitamin D3 doses 6 times higher than white people (Brenner and Hearing report 2008:540-541)

Additionally, studies show that blacks have bones that are denser and less prone to fractures and osteoporosis than whites (report O'connor et al., 2003:263)which should not be the case if we are generally deficient in vitamin D.

This should impress upon us the importance of considering race and ethnicity in the study of the human body and medicine. If you simply take a race-blind approach that assumes everyone is the same, you will inevitably arrive at flawed concepts and practices. This amounts to realizing that white people's vitamin D needs are 6 times greater than black people's.

Furthermore, why rely on data exclusively concerning the white race to determine the biological needs of blacks when we know that in general blacks have fewer diseases and deficiencies than whites, are also more resistant and robust; and this thanks to the antioxidant properties of their melanin. We saw this universally during the covid 19 pandemic. African populations were much less affected than Europeans.


THE BLOOD: Racial Differences in Hemoglobin Concentration: Measurements of Iron, Copper, and Zinc(www.ajcn.org )

It is now scientifically established that blood can be racially or ethnically specific.

Most people are familiar with the eight main blood types: A, B, AB and O, which can each be positive or negative (the Rh factor). These are determined by genes, and which group you are from depends on what combination of proteins and sugars - antigens - cover your red blood cells. The International Society of Blood Transfusion lists 360 known antigens, but the combinations are infinitely more. Many do not affect routine blood transfusion, although all have been discovered due to causing a compatibility issue.


Transfusion

A successful blood transfusion is based on the same principle. If the transfused blood has an antigen that you are missing, your body may react badly. In extremely rare cases, the reaction can be fatal; and even if it doesn't, it can damage the immune system in people who are already weakened by their condition. In addition, you will make an antibody, a kind of immune soldier, which will help to recognize the same antigen better next time. Patients who need regular blood transfusions – those with sickle cell disease, thalassemia or leukemia, for example – continue to create antibodies and may face a decreasing need for appropriate blood because they continue to create antibodies .

We know that not everyone has the same blood, because there are many different types of blood and these types are important for anyone who needs a blood transfusion. Race is important in this context, because people of the same race are more likely to have the same blood type.

Racial Differences in Hemoglobin (Hb) Concentration: Measurements of Iron, Copper, and Zinc


Nutritional surveys have shown that Hb levels in blacks are consistently lower than those in whites. This difference does not appear to be related to socioeconomic dietary differences or differences in inherited disorders such as sickle cell disease. We studied 47 black subjects and 63 white subjects from hospital employees. The average Hb of black men was 0.9 g/dl lower than that of white men. The average Hb of black women was 0.5 g/dl lower than that of white women. This difference was not associated with differences in serum iron, iron binding capacity, or transferrin saturation. White women's ferritin values were significantly lower than values seen in white men, but similar differences were not observed between black men and women. The explanation for this is unclear although it may be related to sample size or differences in menstrual status. Copper levels were lower in white men than in any other group, and zinc levels were essentially similar between racial groups. The red blood cells of blacks were also smaller in quantity than those of whites. This difference could not be explained by disordered Hb synthesis. These observations confirm that Hb concentrations in black men and women are lower than in their white counterparts. This difference cannot be explained by differences in iron, copper or zinc intakes. Furthermore, Hb measurements in nutrition survey populations reflect iron status as only one of many variables and should not be used as the sole assessment of iron nutrition. It is also found that white blood cells are more numerous in whites.


In a large population of African American and white subjects undergoing health screening, we found that whites had higher hematocrit levels, higher hemoglobin levels, higher CVD, higher TS and lower serum ferritin levels than African Americans. The white blood cell count of African Americans was lower, and this difference was mainly due to a decrease in the number of granulocytes, whereas the absolute lymphocyte count was actually higher among African Americans. These data were consistent with the observations of others (see Perry et al2 for a detailed review of hemoglobin data). Although it has been proposed that the difference in hemoglobin levels may be mainly due to socioeconomic and nutritional factors, most studies suggest that there are other causes, most likely genetic, that account for the difference. . Perry et al2 provided evidence that the difference in hemoglobin is not due to iron deficiency. High levels of serum ferritin have been found in African Americans in previous studies. Although the cause of this difference between African American and white subjects is not fully understood, it is likely to have a genetic basis, as familial segregation of ferritin levels has been demonstrated in Africans.


From these observations one could deduce that in general the biological needs of whites would be higher than those of blacks.

However, we must not forget that the antioxidant melanin playing a significant role in the fight against free radicals is very present in the blood, organs, tissues of blacks, unlike whites. Couldn't these biological differences also be explained by its presence?

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